The Remove method deletes the environment variable specified by strName.
WshEnvironment.Remove(strName)
' Delete the EXAMPLE volatile environment variable
Set WshShell = Wscript.CreateObject("Wscript.Shell")
WshShell.Environment("VOLATILE").Remove("EXAMPLE")
' Delete multiple variables
Set WshUsrEnv = Wscript.Environment("User")
WshUsrEnv.Remove("EXAMPLE_1")
WshUsrEnv.Remove("EXAMPLE_2")
WshUsrEnv.Remove("EXAMPLE_3")
WshUsrEnv.Remove("EXAMPLE_4")