You can use the AppDelete method of the IIsWebVirtualDir object to delete a Web application definition from a metabase key. If the application is running, it will be shut down. All resources associated with the application, such as out-of-process packages, will be released. This action cannot be undone.
IIsWebVirtualDir.AppDelete
<%
Dim VDirObj
Set VDirObj = GetObject("IIS://LocalHost/W3SVC/1/ROOT/MyAppVDir")
' Delete the application at this virtual directory
VDirObj.AppDelete
%>
AppCreate, AppDeleteRecursive, AppUnload, AppUnloadRecursive, AppGetStatus, AppDisable, AppDisableRecursive, AppEnable, AppEnableRecursive