After a database has been replicated, you cannot remove the replication features from the database. (Error 3459)

You cannot remove the replication features from a database that has been replicated, either by setting its Replicable property to "T" or by converting it with the Windows Briefcase, Microsoft Access, or the Replication Manager. Using DAO to set the database's Replicable property to "F" or any other value has no effect on the replicated database. If you need to use a copy of the database that does not have the properties, fields, tables, and other characteristics associated with replication, open the backup copy of the database made before the database was first converted.