The debugger requires that the Microsoft® Internet Information Server (IIS) application to be debugged run out of process. This error indicates that the debugger was unable to change an in-process IIS application to run out of process. As a solution, use the IIS management utility (MMC) to set the application to run out of process before starting the debugger.
Currently, your Microsoft® Visual InterDev™ options are set to enable server debugging automatically when you start the debugger. Visual InterDev prompts you to disable these options.
Choose No if you want to maintain these option settings. Choose Yes if you want to turn off these options. In that case, you should set debugger options manually for your IIS applications to be able to debug server script. For details about server debugging options, see Debugging Server Script.