This example adds two rectangles to the first slide in the active presentation, attaches them with a connector, automatically reroutes the connector along the shortest path, and then detaches the connector from the rectangles.
Set myDocument = ActivePresentation.Slides(1)
Set s = myDocument.Shapes
Set firstRect = s.AddShape(msoShapeRectangle, 100, 50, 200, 100)
Set secondRect = s.AddShape(msoShapeRectangle, 300, 300, 200, 100)
With s.AddConnector(msoConnectorCurve, 0, 0, 0, 0).ConnectorFormat
.BeginConnect firstRect, 1
.EndConnect secondRect, 1
.Parent.RerouteConnections
.BeginDisconnect
.EndDisconnect
End With