This example changes the formula for conditional format one for cells E1:E10 if the formula specifies “between 5 and 10"
With Worksheets(1).Range("e1:e10").FormatConditions(1)
If .Operator = xlBetween And _
.Formula1 = "5" And _
.Formula2 = "10" Then
.Modify xlCellValue, xlLess, "10"
End If
End With